LyoPAT II is a combination of Millrock Technology proprietary control packages, giving you the higher performance in a R&D freeze Dryer possible. Currently available on the MicroFD
AccuFlux Heat Flux Measurement
- Direct measurement of shelf surface temperature and Kv during the cycle
- Determine the values for critical process parameters to enable transfer between freeze dryers
- Evaluate the effect of different freezing methods, including Controlled Nucleation, on primary drying
- Evaluate the best post-nucleation heat flow to produce the best crystal structure for your application
- Evaluate the effect of different shelf temperatures and vacuum levels on product temperature and mass flow during primary drying
- Evaluate critical process parameters for different freeze dryers
- Evaluate critical process parameters for application changes, such as vial or product fill
- Develop optimized freezing and primary drying cycles
AutoDry Cycle Optimization
- Feedback directly from product to controller
- Maximize heat input while maintaining product below critical melting temperature during primary drying
- Minimize primary drying cycle
FreezeBooster
- Control nucleation of the free ice
- Create a more homogenous ice matrix across the vials in a single batch
- Control batch to batch freezing uniformity
- Study freezing approaches and its effect on the product and the product cycle
LyoSim
- Simulate/Emulate the conditions of your larger freeze dryer using as few as 19 vials
- Eliminate edge effect with LyoSim to study center vial conditions
- Cycle transfer by design vs simply run time extension